MAXIMUM LIKELIHOOD ANALYSIS OF POPULATION DIFFERENCES IN ALLELIC FREQUENCIES
نویسندگان
چکیده
منابع مشابه
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.
Molecular techniques allow the survey of a large number of linked polymorphic loci in random samples from diploid populations. However, the gametic phase of haplotypes is usually unknown when diploid individuals are heterozygous at more than one locus. To overcome this difficulty, we implement an expectation-maximization (EM) algorithm leading to maximum-likelihood estimates of molecular haplot...
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ژورنال
عنوان ژورنال: Genetics
سال: 1972
ISSN: 1943-2631
DOI: 10.1093/genetics/72.4.709